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Cholangiocarcinoma
Cross-Comparison of Clinical Trials Assessing Futibatinib and Pemigatinib versus Chemotherapy in Patients with CCA and FGFR2 Fusion or Other Rearrangements
Cholangiocarcinoma
2022 Year in Review: Cholangiocarcinoma
— January 4, 2023
A comparison of clinical trials found progression-free survival with futibatinib to be significantly greater compared with chemotherapy and that trials favor futibatinib over pemigatinib for all efficacy parameters.
Read More
Utility of Liquid Biopsy for Identification of Molecular Alterations in Solid Tumors
Cholangiocarcinoma
2022 Year in Review: Cholangiocarcinoma
— January 4, 2023
Real-world evidence supports a role for liquid biopsy in identifying molecular alterations and offering personalized treatment options, with
IDH1
identified in a patient with cholangiocarcinoma.
Read More
Preliminary Analyses of QOL Data from the ABC-06 Clinical Trial
Cholangiocarcinoma
2022 Year in Review: Cholangiocarcinoma
— January 4, 2023
Preliminary quality-of-life data suggest a potentially positive impact of L-folinic acid plus oxaliplatin plus 5-fluorouracil when used in conjunction with active symptom control.
Read More
NALIRICC Study of Nanoliposomal Irinotecan Combination Therapy in Metastatic BTC
Cholangiocarcinoma
2022 Year in Review: Cholangiocarcinoma
— January 4, 2023
The NALIRICC study did not meet overall survival or progression-free survival end points, with nanoliposomal irinotecan plus 5-fluorouracil falling short in patients with metastatic biliary tract cancer.
Read More
Tislelizumab plus GemOx and Lenvatinib as a Conversion Therapy Regimen for Potentially Resectable BTCs
Cholangiocarcinoma
2022 Year in Review: Cholangiocarcinoma
— January 4, 2023
The combination of tislelizumab, lenvatinib, and gemcitabine/oxaliplatin was shown to be promising as a conversion therapy for patients with potentially resectable locally advanced biliary tract cancer in this phase 2 study.
Read More
Health-Related QOL Study in Patients with CCA
Cholangiocarcinoma
2022 Year in Review: Cholangiocarcinoma
— January 4, 2023
Study revealed increased financial toxicities in patients with cholangiocarcinoma enrolled in clinical trials and receiving targeted therapies.
Read More
Updated Analysis of the LUC2001 Study
Cholangiocarcinoma
2022 Year in Review: Cholangiocarcinoma
— January 4, 2023
Erdafitinib was found to be associated with durable efficacy and manageable toxicity in Asian patients with advanced cholangiocarcinoma with
FGFR
alterations.
Read More
Biliary Tract Cancers: Is Laparoscopic Liver Resection Adequate?
Cholangiocarcinoma
2022 Year in Review: Cholangiocarcinoma
— January 4, 2023
Study finds laparoscopic liver resection was associated with less blood loss and shorter length of stay compared with open liver resection.
Read More
The Future of Neoadjuvant Chemotherapy for iCCA
Cholangiocarcinoma
2022 Year in Review: Cholangiocarcinoma
— January 4, 2023
Study found lower rates of margin-positive resection of intrahepatic cholangiocarcinoma with neoadjuvant chemotherapy.
Read More
Mayo Clinic Study Assessed Impact of Neoadjuvant Chemoradiation in Patients with Unresectable Perihilar CCA
Cholangiocarcinoma
2022 Year in Review: Cholangiocarcinoma
— January 4, 2023
Neoadjuvant chemoradiation was found to elicit no differences in survival among patients with unresectable perihilar cholangiocarcinoma.
Read More
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