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Cholangiocarcinoma
Risk Factors for Early Relapse in Patients Undergoing Curative Resection in JCOG1202 Subgroup Analysis
Cholangiocarcinoma
In the JCOG1202 subgroup analysis, researchers analyzed risk factors for early relapse in patients with biliary tract cancer undergoing surgical resection.
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Characteristics of Long-Term Survivors in the TOPAZ-1 Trial
Cholangiocarcinoma
Researchers aimed to assess characteristics, outcomes, and genomic profiles of long-term survivors treated with durvalumab plus gemcitabine/cisplatin (GemCis) or placebo plus GemCis in the TOPAZ-1 trial.
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IMbrave 151: Atezolizumab With or Without Bevacizumab in Combination With GemCis in Advanced BTC
Cholangiocarcinoma
IMbrave 151 examined the efficacy of the PD-L1 inhibitor atezolizumab with or without the VEGF inhibitor bevacizumab, and gemcitabine/cisplatin as first-line treatments in patients with advanced biliary tract cancer.
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Nab-Paclitaxel Plus Sintilimab as Second-Line Treatment for Patients With Advanced BTC: A Phase 2 Study
Cholangiocarcinoma
A single-arm, phase 2 study investigated the safety and efficacy of second-line nab-paclitaxel combined with the anti–PD-1 antibody sintilimab in patients with advanced biliary tract cancer.
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Phase 2 Trial of Nivolumab With or Without Ipilimumab Plus SBRT in Patients With Pretreated Advanced BTC
Cholangiocarcinoma
This phase 2 randomized trial assessed stereotactic body radiation and the anti–PD-1 drug nivolumab with or without the anti-CTLA4 drug ipilimumab in patients with metastatic biliary tract cancer.
Read More
The Cost-Effectiveness of GemCis With or Without Durvalumab in Patients With Advanced CCA
Cholangiocarcinoma
This study examined the costs of treatment with gemcitabine/cisplatin with or without durvalumab in patients with advanced cholangiocarcinoma.
Read More
NUC-1031 Plus Cisplatin Versus GemCis for First-line Treatment of Advanced BTC, NuTide: 121
Cholangiocarcinoma
In the phase 3 Nutide:121 study, NUC-1031 plus cisplatin was compared with gemcitabine/cisplatin for first-line treatment of patients with advanced biliary tract cancer.
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Cross-Comparison of Clinical Trials Assessing Futibatinib and Pemigatinib versus Chemotherapy in Patients with CCA and FGFR2 Fusion or Other Rearrangements
Cholangiocarcinoma
A comparison of clinical trials found progression-free survival with futibatinib to be significantly greater compared with chemotherapy and that trials favor futibatinib over pemigatinib for all efficacy parameters.
Read More
Utility of Liquid Biopsy for Identification of Molecular Alterations in Solid Tumors
Cholangiocarcinoma
Real-world evidence supports a role for liquid biopsy in identifying molecular alterations and offering personalized treatment options, with
IDH1
identified in a patient with cholangiocarcinoma.
Read More
Preliminary Analyses of QOL Data from the ABC-06 Clinical Trial
Cholangiocarcinoma
Preliminary quality-of-life data suggest a potentially positive impact of L-folinic acid plus oxaliplatin plus 5-fluorouracil when used in conjunction with active symptom control.
Read More
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