CCA Summit Conference Correspondent

Although surgical resection has curative potential in intrahepatic cholangiocarcinoma, duration of long-term cure is low due to a high rate of recurrences, which may require locoregional and systemic therapies for disease management.
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Current evidence supports the use of radioembolization in intrahepatic cholangiocarcinoma based on data showing that the addition of locoregional therapy prolongs survival and can downstage select patients to curative resection.
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Liver-directed therapies have shown promise for first-line treatment of intrahepatic cholangiocarcinoma; however, it requires careful patient selection and institutional experience.
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Pashtoon Kasi, MD, MS, discussed the use of liquid biopsy molecular profiling to identify actionable alterations and provide opportunities for precision medicine in patients with advanced cancers including cholangiocarcinoma.
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Cristine R. Ferrone, MD, discussed the perioperative integration of neoadjuvant and adjuvant therapy with medical oncologists in the management of cholangiocarcinoma.
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